Characterization of the 5-HT4 receptor mediating tachycardia in piglet isolated right atrium
نویسندگان
چکیده
منابع مشابه
Selective desensitization of the 5-HT4 receptor-mediated response in pig atrium but not in stomach.
BACKGROUND AND PURPOSE The time dependency of the effect of 5-HT(4) receptor agonists depends on many specific regulatory mechanisms, which vary between tissues. This has important implications with regard to the effects of endogenous 5-HT, as well as to the clinical use of 5-HT(4) receptor agonists, and might contribute to tissue selectivity of agonists. EXPERIMENTAL APPROACH The progression...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1993
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1993.tb13916.x